Week 3 fantasy starts hinge on injury updates and high-volume targets. Jauan Jennings’ ankle status could push Ricky Pearsall into a larger role, while Tetairoa McMillan continues as Carolina’s top target with a robust Week 2 workload. Jaylen Warren’s pass-game involvement points to solid RB2 production, and DK Metcalf is a buy-low candidate with tangible upside as Pittsburgh filters in more passes. The piece highlights the Who Should I Start tool to optimize four-player comparisons and unlock precise, matchup-driven decisions for Week 3.

Expect a mix of floor versus ceiling in Week 3: McMillan and Pearsall offer reliable targets, Jennings’ status dictates Cardinals-upside, and Metcalf represents a pivotal buy-low anchor as the Steelers chase offensive consistency. The analysis threads through each listed player—Jennings, Moore, McMillan, Dobbins, Warren, Pearsall, Smith, Swift, Meyers, Metcalf—clarifying who should start, who could disappoint, and where upside hides in Week 3 matchups.

Week 3 brings Seattle as 7.5-point favorites at home against New Orleans, but injuries to Devon Witherspoon and Nick Emmanwori could blunt Seattle’s secondary edge. Spencer Rattler and the Saints offense have found traction, and the SportsLine model assigns a 38% upset chance for New Orleans—a surprisingly credible figure for a road test. The model’s Week 3 survivor pick diverges from Seattle, suggesting a one-score outcome with Seattle at about 62% win probability.

The slate features seven 5+ point spreads, including Dolphins-Bills, Packers-Browns, Falcons-Panthers, Jets-Bucs, Saints-Seahawks, Chiefs-Giants, and Lions-Ravens, underscoring how survivor players will chase value. The model touts a long, earned track record (10,000 simulations, 37-17 on top picks since 2024) and is the guiding beacon for those locking Week 3 picks, with promos noted for new users.

Buffalo vaults to 2-0 behind a flexible attack: a shootout in Week 1 led by Josh Allen and the run game, then a ground-heavy follow-up that kept the Jets at bay. Allen sits near the top of QB rankings, second only to Lamar Jackson, as Buffalo readies a primetime test vs Miami. With Miami 0-2, the Bills can push their AFC East grip to 3-0 and widen the distance in a potential playoff tilt.

Fantasy eyes stay glued to Allen’s dual threat and to how James Cook complements a leaky run defense. Allen’s mix of passing efficiency and rushing upside makes him a high-ceiling play in Week 3 against Miami, while Buffalo’s defense aims to stymie a division rival’s push. The narrative: Bills as division bullies, with Allen leading the charge in a must-watch showdown.

AFC North Week 3 spotlight centers on Baltimore’s primetime clash with Detroit after a 1-1 start, while Cleveland hosts Green Bay and Cincinnati navigates Burrow’s absence with Browning. Pittsburgh travels to New England as Drake Maye leads a younger Patriots’ attack. Minnesota’s Flores-helmed defense faces Browning and a leaned-on Vikings offense, setting the stage for a week of fantasy pivots and player-by-player decisions.

Run-heavy Browns, explosive Ravens passing, and a QB-by-committee Bengals offense shape Week 3. Expect Hopkins and Jefferson to anchor big-play ceilings, while Judkins and Browning carry meaningful week-to-week fantasy risk/reward. The slate tests depth and matchup-driven upside across offenses and defenses alike.

Thursday night’s Dolphins–Bills clash fuels bold fantasy daydreams: fans would steal Buffalo stars for Miami, even musing about swapping QB, coach, and lineup pieces. Josh Allen tops the wishlist, while Spencer Brown at right tackle emerges as the clearest on-field steal for a quick fantasy lift.

Predictions skew Buffalo-heavy, with a 47-17 blowout cited by some and others warning of Bills dominance on time of possession and the run game. Tua Tagovailoa and Lamar Jackson pop up in conversations, and McDermott’s coaching is cited as a key variable shaping fantasy upside in this rivalry.